Endocrine Abstracts

Introduction: In recent years, the technique of ASG has gained much in simplicity, speed and acceptability, using readers more and more reliable. Despite this, some patients do not acquire the skills needed to achieve it. The aim of this study is to evaluate the technical gestures of use of blood glucose readers in current practice.Material and method: This is a prospective descriptive study including 369 diabetics for over a year, followed in diabetic c...

Lymphoma adrenal is a rare cause of adrenal tumor (0.5%). Bilateral primary lymphoma adrenal phenotype T is exceptional. We report two observations. MO 56 years old was hospitalized FOR exploration and therapeutic management of two large adrenal masses discovered on CT imaging after back pain, and weight loss. Physical examination revealed a patient asthenic, with no signs of hypersecretion. The rest of the examination was unremarkable and research call signs primary neoplasm ...

Introduction: Suppurative meningitis (SM) is a life threatening disease. It is rarely observed as a primary presentation in large pituitary tumours (PT) destroying the sellar floor and/or invading the skull base. Our aim is to report 3 SM revealing macroprolactinomas.Case No. 1: A man aged 22, consulted for vomiting and fever. The diagnosis of SM was confirmed by lumbar puncture and blood cultures. Cerebral MRI showed multidirectional PT invading caverno...

Introduction: Acromegaly is a relatively rare disease with numerous complications. Our aim is to look for visceral abnormalities and tumour development in subjects with GH and insuIin like GH (or IGF1) excess.Subjets and methods: It is a retro-and prospective study that takes in account 112 patients at diagnosis, with pur pituitary tumours secreting GH, or mixed tumours secreting prolactin and GH diagnosed between 1980 and 2012. They all were questioned ...

Introduction: Generously supported by IPSEN)-->Pituitary tumours are known to cause headaches and visual troubles by compressing pituitary adjacent structures. Pressure on more distant structures is exceptional. In very large tumours such as prolactinomas, mixed adenomas or craniopharyngiomas, hydrocephalus, convulsions, memory troubles and even unconsciousness can be observed, but to our best knowledge motor deficits, such as hemipl...

Introduction: Prolactinomas are more invasive in males. Giant ones (height ≥4 cm) are relatively rare in literature.Our aim is to analyze their frequency, their radiological aspects, and their neurological, endocrine and ophthalmological complications.Methods: All of them had clinical exam, hormonal, ophthalmological, and radiological assessment based on cerebral MRI. Mixed adenomas were excluded. Positive diagnosis was based...

Introduction: Cardiothyreosis is a severe and most frequent heart complication due to hyperthyroidism. It includes severe arrhythmias, heart insufficiency or heart coronary insufficiency ± atrial ventricular block, or pulmonary hypertension.Our aim was to study cardiothyreosis frequency in females, its incidence, its causes, and its response to radical treatment.Subjects and methods: It is a retro-and prospective study which a...

Introduction: Cardiothyreosis (CT) is the most frequent and dangerous complication of hyperthyroidism (HT). It is defined as an association of HT with severe heart abnormalities such: rhythmic troubles, heart and/or coronary insufficiency, atrio-ventricular block, and arterial pulmonary hypertension.Our aim was to study its frequency, in Algerian population, analyze its profile and its response to radical treatment.Materials and me...

Introduction: Glucose metabolism disorders are well known in subjects with GH excess, but little is known about other metabolic abnormalities. Our aim is to analyze metabolic complications in subjects with acromegaly and pituitary gigantism.Subjects and methods: Records of 111 subjects were retrospectively examined, mean GH=62 ng/ml (n<5), mean age=39.11 (14–60). All had routine analysis for fasting blood glucose, cholesterol, triglycer...

Introduction: These last years have seen emerger identification of a large number of genes responsible of bone disease. La dyschondrosteosis: Leri weill is more important to know. It include short stature due to moderate micromelia mesomelic associated with a very characteristic deformity of the wrist: the Madelung deformity. This pathology is caused by haploinsufficiency of the SHOX gene, a gene essential in regulating the growth and remodeling of skeletal. We report observat...